332 0 obj <> endobj Extravasation refers to the leakage of injected drugs from blood vessels causing damage to the surrounding tissues. 1. Distributed by: Common non-antineoplastic drugs that can act as vesicants or irritants [Internet] [cited 2020 Jul 10]. A 24 hour continuous infusion of diltiazem hydrochloride injection in the treatment of atrial fibrillation or atrial flutter maintained at least a 20% heart rate reduction during the infusion in 83% of patients. Your doctor may occasionally change your dose. Medically reviewed by Kaci Durbin, MD. These antiarrhythmic agents were intravenous or oral digoxin, Class 1 antiarrhythmics (e.g., quinidine, procainamide), calcium channel blockers, and oral beta-blockers. Reduction in mean arterial pressure correlated linearly with diltiazem plasma concentration in a group of hypertensive patients. In the controlled clinical trials, 3.2% of patients required some form of intervention (typically, use of intravenous fluids or the Trendelenburg position) for blood pressure support following diltiazem hydrochloride injection. This content does not have an English version. Nervous System: Dizziness, paresthesia FOIA Do NOT flush the line with normal saline or dextrose High blood pressure adds to the workload of the heart and arteries. This document is only valid for the day on which it is accessed. Donate. Paroxysmal supraventricular tachycardia - Clinical studies of diltiazem hydrochloride injection for PSVT did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients. The patients normal activities, such as at home, work, school, etc., may be disrupted until the patient is fully recovered. Diltiazem | RxWiki Extravasation may occur if the administration of the drug is too quick, the medication is very acidic or basic, or there is an obstruction in the . If response is inadequate, a second dose may be administered after 15 minutes.
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